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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-4-17
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pubmed:abstractText |
Intravesical adenovirus mediated interferon-alpha gene transfer has a potent therapeutic effect against superficial human bladder carcinoma xenografts growing in the bladder of athymic nude mice. We determined whether the inhibition of angiogenesis might contribute to the antitumor effect.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-alpha,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 2,
http://linkedlifedata.com/resource/pubmed/chemical/NF-kappa B,
http://linkedlifedata.com/resource/pubmed/chemical/Proto-Oncogene Proteins c-myb,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-1,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factor AP-2,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/interferon alfa-2b
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-5347
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1900-6
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17437845-Adenoviridae,
pubmed-meshheading:17437845-Animals,
pubmed-meshheading:17437845-Antineoplastic Agents,
pubmed-meshheading:17437845-Blotting, Western,
pubmed-meshheading:17437845-Cell Line, Tumor,
pubmed-meshheading:17437845-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17437845-Gene Therapy,
pubmed-meshheading:17437845-Genetic Vectors,
pubmed-meshheading:17437845-Humans,
pubmed-meshheading:17437845-Immunohistochemistry,
pubmed-meshheading:17437845-Interferon-alpha,
pubmed-meshheading:17437845-Matrix Metalloproteinase 2,
pubmed-meshheading:17437845-Mice,
pubmed-meshheading:17437845-Mice, Nude,
pubmed-meshheading:17437845-Microscopy, Confocal,
pubmed-meshheading:17437845-NF-kappa B,
pubmed-meshheading:17437845-Neovascularization, Pathologic,
pubmed-meshheading:17437845-Proto-Oncogene Proteins c-myb,
pubmed-meshheading:17437845-RNA, Neoplasm,
pubmed-meshheading:17437845-Recombinant Proteins,
pubmed-meshheading:17437845-Transcription Factor AP-1,
pubmed-meshheading:17437845-Transcription Factor AP-2,
pubmed-meshheading:17437845-Urinary Bladder Neoplasms,
pubmed-meshheading:17437845-Vascular Endothelial Growth Factor A
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pubmed:year |
2007
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pubmed:articleTitle |
Adenoviral mediated interferon-alpha 2b gene therapy suppresses the pro-angiogenic effect of vascular endothelial growth factor in superficial bladder cancer.
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pubmed:affiliation |
Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA. ladam@mdanderson.org
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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