Source:http://linkedlifedata.com/resource/pubmed/id/17435996
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2007-10-24
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pubmed:abstractText |
In patients with medullary thyroid carcinoma (MTC), rising levels of the tumour markers calcitonin and CEA after primary surgery indicate tumour recurrence or metastases. The only chance of cure is the resection of localised tumour tissue. For positron emission tomography (PET) with (18)F-fluorodeoxyglucose ((18)F-FDG) and (18)F-dihydroxyphenylalanine ((18)F-DOPA), sensitivities of 78% and 63% have been reported, but in a considerable percentage of MTC patients the source of tumour marker elevation is not detected. The aim of this retrospective data evaluation was to compare the value of PET with (18)F-FDG, (18)F-DOPA and the amino acid tracer 3-O-methyl-6-[(18)F]fluoro-DOPA ((18)F-OMFD) in the detection of MTC recurrence.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/3-O-methyl-6-fluoro-dopa,
http://linkedlifedata.com/resource/pubmed/chemical/Dihydroxyphenylalanine,
http://linkedlifedata.com/resource/pubmed/chemical/Fluorodeoxyglucose F18,
http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals,
http://linkedlifedata.com/resource/pubmed/chemical/fluorodopa F 18
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
1619-7070
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1604-9
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pubmed:meshHeading |
pubmed-meshheading:17435996-Adult,
pubmed-meshheading:17435996-Aged,
pubmed-meshheading:17435996-Carcinoma, Medullary,
pubmed-meshheading:17435996-Dihydroxyphenylalanine,
pubmed-meshheading:17435996-Female,
pubmed-meshheading:17435996-Fluorodeoxyglucose F18,
pubmed-meshheading:17435996-Humans,
pubmed-meshheading:17435996-Male,
pubmed-meshheading:17435996-Middle Aged,
pubmed-meshheading:17435996-Neoplasm Recurrence, Local,
pubmed-meshheading:17435996-Radiopharmaceuticals,
pubmed-meshheading:17435996-Reproducibility of Results,
pubmed-meshheading:17435996-Sensitivity and Specificity,
pubmed-meshheading:17435996-Thyroid Neoplasms
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pubmed:year |
2007
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pubmed:articleTitle |
Diagnostic impact of PET with 18F-FDG, 18F-DOPA and 3-O-methyl-6-[18F]fluoro-DOPA in recurrent or metastatic medullary thyroid carcinoma.
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pubmed:affiliation |
Department of Nuclear Medicine, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden and PET-Center Dresden-Rossendorf, Fetscherstrasse 74, 01307 Dresden, Germany. b.beuthien@fz-rossendorf.de
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pubmed:publicationType |
Journal Article,
Comparative Study,
Evaluation Studies
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