Linked Life Data

17432945

Source:http://linkedlifedata.com/resource/pubmed/id/17432945

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-4-16
pubmed:abstractText
Specific markers for Coxiella burnetii (C.b.) isolates RSA 493, Priscilla, and BUD were detected using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). The method revealed noticeable differences in the ion signal profiles of the isolates in the mass range of 318 kDa. The number of characteristic ions for RSA 493, BUD, and Priscilla was 24, 15, and 7, respectively. The specific markers were compared against C.b. database using the Tag-Ident proteomics tool. For the isolates RSA 493, Priscilla and BUD there were identified 11, 5 and 3 potential biomarkers, respectively. This method represents a powerful tool for the rapid, sensitive, and differential characterization of C.b. isolates and is a good candidate for phyloproteomic approaches.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-723X
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
55-8
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Detection of specific spectral markers of Coxiella burnetii isolates by MALDI-TOF mass spectrometry.
pubmed:affiliation
Institute of Virology, Slovak Academy of Sciences, Bratislava, Slovak Republic.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't