Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2007-4-13
pubmed:abstractText
Guillain-Barré syndrome (GBS) is an acute self-limited motor-dominant neuropathy, in which autonomic nervous system is frequently involved. Cardiovascular complications, such as hypertension, hypotension, bradyarrhythmias, and tachyarrythmias, are particularly important because they are sometimes life-threatening. Antiganglioside antibodies are frequently present in the acute-phase sera of GBS. They are considered to be useful for diagnosis and to be involved in the pathogenetic mechanisms. No association between autonomic dysfunction and antiganglioside antibody however has been reported. Recently, we performed the quantitative sudomotor axon reflex test (QSART) in GBS patients and found that patients with high scores in QSART had anti-GQ1b IgG antibodies. It indicates the association between postganglionic sudomotor dysfunction and anti-GQ1b antibodies. Further investigation on larger number of patients is needed to clarify the role of antiganglioside antibodies in the development of autonomic dysfunction.
pubmed:language
jpn
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0009-918X
pubmed:author
pubmed:issnType
Print
pubmed:volume
46
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
878-80
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[Autonomic involvement in Guillain-Barré syndrome].
pubmed:affiliation
Department of Neurology, Kinki Univerisity School of Medicine.
pubmed:publicationType
Journal Article, English Abstract