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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1992-1-10
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pubmed:abstractText |
New methods that will be useful in the study of the pharmacokinetics of both new and established antiepileptic drugs include stable-isotope tracer techniques for studies of absorption, elimination, and drug interactions; the microperfusion technique and the staggered stable-isotope administration technique for the study of distribution; and the correction of trough drug serum concentration values to mean serum concentration values. New pharmacokinetic methods for a study of drugs with new and unique properties include a double stable-isotope technique to deal with the unique pharmacokinetic properties of prodrugs and techniques for describing the biologic half-life of drugs that have a high affinity for active sites.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0013-9580
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32 Suppl 5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S66-73
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pubmed:dateRevised |
2005-11-16
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pubmed:meshHeading |
pubmed-meshheading:1743172-Absorption,
pubmed-meshheading:1743172-Anticonvulsants,
pubmed-meshheading:1743172-Brain,
pubmed-meshheading:1743172-Brain Chemistry,
pubmed-meshheading:1743172-Dialysis,
pubmed-meshheading:1743172-Epilepsy,
pubmed-meshheading:1743172-Half-Life,
pubmed-meshheading:1743172-Humans,
pubmed-meshheading:1743172-Isotope Labeling,
pubmed-meshheading:1743172-Perfusion,
pubmed-meshheading:1743172-Pharmacokinetics
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pubmed:year |
1991
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pubmed:articleTitle |
New pharmacokinetic methods for the study of antiepileptic medications of the 1990s.
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pubmed:affiliation |
Department of Neurology, Boston University School of Medicine, MA 02118.
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pubmed:publicationType |
Journal Article,
Review
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