Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2010-6-28
pubmed:abstractText
Calf-related drug use was studied on 104 randomly selected Holstein dairy farms in southwestern Ontario between October 1980 and July 1983. About 20% of dairy farmers were observed to administer antimicrobials preventively to healthy newborn calves (primarily as commercial "cocktails" of various antimicrobials, vitamins and minerals given in an oral bolus form) at some time during the year. About 30% of the farmers were observed to use vitamins (primarily vitamins A,D and E) preventively. The pattern of types of antimicrobials used preventively appeared to be different from the pattern seen for therapeutic use. Chloramphenicol was the single most commonly used therapeutic antimicrobial in this population of calves, accounting for some 30% of overall therapeutic antimicrobial use. In this study population, the prophylactic use of antimicrobials was associated with a decreased risk of being treated for pneumonia, and of dying, but an increased risk of being treated for scours. Case fatality rates for calves treated therapeutically varied, depending on the antimicrobial used and the routine of treatment. Calves treated with penicillin consistently suffered the highest case fatality rates. Case fatality rates for calves treated with chloramphenicol were considerably higher for calves treated once per day than for calves treated twice per day. For instance, calves first treated for scours with chloramphenicol, if treated once per day, suffered a case fatality rate of 22%. For scouring calves treated twice per day the case fatality rate was just under five percent. Clinical field trials of specific antimicrobials used preventively and therapeutically are required to delineate the conditions under which they might be useful.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Jan
pubmed:issn
0008-5286
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
17-22
pubmed:dateRevised
2010-9-15
pubmed:year
1986
pubmed:articleTitle
Calf-related Drug Use on Holstein Dairy Farms in Southwestern Ontario.
pubmed:publicationType
Journal Article