| pubmed-article:17420455 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C1257890 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C0205102 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C0021920 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C0242850 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C0441587 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C1705818 | lld:lifeskim |
| pubmed-article:17420455 | lifeskim:mentions | umls-concept:C0851166 | lld:lifeskim |
| pubmed-article:17420455 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:17420455 | pubmed:dateCreated | 2007-4-18 | lld:pubmed |
| pubmed-article:17420455 | pubmed:abstractText | Mobile DNAs use many mechanisms to minimize damage to their hosts. Here we show that a subclass of group II introns avoids host damage by inserting directly after transcriptional terminator motifs in bacterial genomes (stem-loops followed by Ts). This property contrasts with the site-specific behavior of most group II introns, which insert into homing site sequences. Reconstituted ribonucleo protein particles of the Bacillus halodurans intron B.h.I1 are shown to reverse-splice into DNA targets in vitro but require the DNA to be single-stranded and fold into a stem-loop analogous to the RNA structure that forms during transcription termination. Recognition of this DNA stem-loop motif accounts for in vivo target specificity. Insertion after terminators is a previously unrecognized strategy for a selfish DNA because it prevents interruption of coding sequences and restricts expression of the mobile DNA after integration. | lld:pubmed |
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| pubmed-article:17420455 | pubmed:language | eng | lld:pubmed |
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| pubmed-article:17420455 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:17420455 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17420455 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:17420455 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:17420455 | pubmed:author | pubmed-author:SeoWooseokW | lld:pubmed |
| pubmed-article:17420455 | pubmed:author | pubmed-author:ZimmerlySteve... | lld:pubmed |
| pubmed-article:17420455 | pubmed:author | pubmed-author:RobartAaron... | lld:pubmed |
| pubmed-article:17420455 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17420455 | pubmed:day | 17 | lld:pubmed |
| pubmed-article:17420455 | pubmed:volume | 104 | lld:pubmed |
| pubmed-article:17420455 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17420455 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17420455 | pubmed:pagination | 6620-5 | lld:pubmed |
| pubmed-article:17420455 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:17420455 | pubmed:meshHeading | pubmed-meshheading:17420455... | lld:pubmed |
| pubmed-article:17420455 | pubmed:meshHeading | pubmed-meshheading:17420455... | lld:pubmed |
| pubmed-article:17420455 | pubmed:meshHeading | pubmed-meshheading:17420455... | lld:pubmed |
| pubmed-article:17420455 | pubmed:meshHeading | pubmed-meshheading:17420455... | lld:pubmed |
| pubmed-article:17420455 | pubmed:meshHeading | pubmed-meshheading:17420455... | lld:pubmed |
| pubmed-article:17420455 | pubmed:meshHeading | pubmed-meshheading:17420455... | lld:pubmed |
| pubmed-article:17420455 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17420455 | pubmed:articleTitle | Insertion of group II intron retroelements after intrinsic transcriptional terminators. | lld:pubmed |
| pubmed-article:17420455 | pubmed:affiliation | Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, AB, Canada T2N 1N4. | lld:pubmed |
| pubmed-article:17420455 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:17420455 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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