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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-4-9
pubmed:abstractText
Plasma membrane proteins play a key role in cellular processes such as migration, adhesion, and cell survival. The comprehensive annotation of the leukemic cell plasma membrane proteome allows the identification of proteins that may be involved in the pathogenesis of disease and may provide novel therapeutic targets. The identification of known adhesion molecules or novel proteins with similar attributes to adhesion molecules provides the starting point for the generation of hypothesis on the role of these proteins in adhesion processes. In order to identify these novel proteins, we have developed a proteomics methodology using purified plasma membranes prepared from human leukemic cells.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
1064-3745
pubmed:author
pubmed:issnType
Print
pubmed:volume
370
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-46
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Proteomic analysis of cell surface membrane proteins in leukemic cells.
pubmed:affiliation
Proteomics Facility, MRC Toxicology Unit, University of Leicester, Leicester, UK.
pubmed:publicationType
Journal Article