Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-3-23
pubmed:abstractText
Tomato telomeres are composed of a terminal 7-base-pair tandem repeat and a closely liked 162-base-pair subtelomeric repeat (TGRI). Together, these repeats account for 2% of the total chromosomal DNA. Pulsed-field gel electrophoresis has been used to examine the long-range physical structure of these arrays in closely related varieties, and we report here that these arrays are undergoing heritable changes at a frequency as great as 2% per generation. Moreover, comparisons with other known hypervariable probes (e.g., human minisatellites and M13 sequences) revealed that telomeric sites are more variable than any other known region of the plant genome and can be used to distinguish closely related plant varieties (tomato and melon) that are otherwise very similar at the DNA level. The fact that the polymorphisms are inherited in a mendelian fashion suggests applications in genetic mapping of telomeres and identification of varieties.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-1668615, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-1977657, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2170845, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2175882, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2342578, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2392154, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2870519, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2880398, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-2901106, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-291943, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-3347271, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-3349525, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-3538420, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-3856104, http://linkedlifedata.com/resource/pubmed/commentcorrection/1741387-7110332
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0027-8424
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
89
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1354-7
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Telomeric arrays display high levels of heritable polymorphism among closely related plant varieties.
pubmed:affiliation
Department of Plant Breeding and Biometry, Cornell University, Ithaca, NY 14853.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, Non-P.H.S., Research Support, Non-U.S. Gov't