Linked Life Data

17412523

Source:http://linkedlifedata.com/resource/pubmed/id/17412523

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2007-6-4
pubmed:abstractText
Circadian clock genes have been identified in humans but information regarding their expression has remained very limited. However from a basic point as well as in a diagnostic and therapeutic perspective, it is important to evaluate molecular clock gene expression. Peripheral blood mononuclear cells represent an ideal material to investigate non-invasively the human clock at the molecular level. Several studies including ours reported rhythmic expression of clock genes in these cells, with significant intersubject variability of expression. In addition, our results reveal the existence of different chronotypes of clock gene expression patterns and suggest specific regulatory mechanisms in these human cells as compared to other peripheral tissues.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0369-8114
pubmed:author
pubmed:issnType
Print
pubmed:volume
55
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
208-10
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:articleTitle
[Circadian clock gene expression in human peripheral blood mononuclear cells].
pubmed:affiliation
Université de Nice - Sophia-Antipolis, CNRS UMR 6548, parc Valrose, 06108 Nice, France. teboulm@unice.fr
pubmed:publicationType
Journal Article, English Abstract