Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-3-23
pubmed:abstractText
Liposome-encapsulated fluorescent dye has been altered to allow full fundus angiography after a single laser shot. By exposing the retinal arteries to laser energy where they emerge at the optic disc nerve head, dye release is elicited simultaneously in all four quadrants of the retina, without choroidal fluorescence, allowing visualization of the retinal microcirculation. Because the quantity of dye release is limited, recirculation does not increase background fluorescence. The procedure can be repeated many times without delay with consistent results. Increasing the laser spot size to 1.5 mm allows consistent dye release at energy densities from 0.5 J/cm2 to 3.4 J/cm2. This refinement will allow direct comparison in primates of this technique and conventional fluorescein angiography. The laser energy delivered to the retina is below suggested levels that may be tolerated by the optic nerve.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0161-6420
pubmed:author
pubmed:issnType
Print
pubmed:volume
99
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
72-9
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Laser-triggered repetitive fluorescein angiography.
pubmed:affiliation
LSU Eye Center, Louisiana State University Medical Center School of Medicine, New Orleans 70112-2234.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S.