Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2007-4-5
pubmed:abstractText
Preoperative and intraoperative lymph node (LN) staging is of paramount importance for patients with non-small cell lung cancer. The Council of the European Society of Thoracic Surgery took the initiative to organize workshops on intraoperative and preoperative mediastinal LN staging. This resulted in specific guidelines. Relevant peer-reviewed publications on these subjects, the experience of the participants, and the opinion of the European Society of Thoracic Surgery members contributing online were used to reach a consensus. For primary staging, mediastinoscopy remains the gold standard for the superior mediastinal LNs. Invasive procedures can be omitted in patients with peripheral tumors and negative mediastinal and hilar nodes on positron emission tomography scan. Positron emission tomography-positive mediastinal findings should always be cytohistologically confirmed. New minimally invasive techniques that provide cytohistological diagnosis became available. Their specificity is high, but the negative predictive value is low. If they yield negative results, an invasive surgical technique remains indicated. For restaging, invasive techniques providing cytohistological information are advisable. Systematic nodal dissection is recommended in all cases to ensure complete resection. Lobe-specific systematic nodal dissection is acceptable for peripheral squamous T1 tumors if hilar and interlobar nodes are negative on frozen section studies. The report from the pathologist should describe the number of LNs removed and studied, the overall number of metastatic LNs in each station, and the status of the LN capsule. We hope that the adherence to these guidelines will standardize and improve preoperative and intraoperative LN staging and pathologic evaluation of non-small cell lung cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1556-1380
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
357-61
pubmed:dateRevised
2008-5-6
pubmed:meshHeading
pubmed-meshheading:17409811-Biopsy, Needle, pubmed-meshheading:17409811-Carcinoma, Non-Small-Cell Lung, pubmed-meshheading:17409811-Europe, pubmed-meshheading:17409811-Female, pubmed-meshheading:17409811-Humans, pubmed-meshheading:17409811-Immunohistochemistry, pubmed-meshheading:17409811-Lung Neoplasms, pubmed-meshheading:17409811-Lymph Node Excision, pubmed-meshheading:17409811-Lymph Nodes, pubmed-meshheading:17409811-Male, pubmed-meshheading:17409811-Mediastinal Neoplasms, pubmed-meshheading:17409811-Mediastinoscopy, pubmed-meshheading:17409811-Monitoring, Intraoperative, pubmed-meshheading:17409811-Neoplasm Staging, pubmed-meshheading:17409811-Pneumonectomy, pubmed-meshheading:17409811-Positron-Emission Tomography, pubmed-meshheading:17409811-Predictive Value of Tests, pubmed-meshheading:17409811-Preoperative Care, pubmed-meshheading:17409811-Sensitivity and Specificity
pubmed:year
2007
pubmed:articleTitle
European trends in preoperative and intraoperative nodal staging: ESTS guidelines.
pubmed:affiliation
Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
pubmed:publicationType
Journal Article, Practice Guideline