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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-4-30
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pubmed:abstractText |
The ability of thyroid cells to take up iodide, which enables (131)I radiotherapy for thyroid cancer, is due to the expression of the sodium iodide symporter at their plasma membrane. Expression of this symporter has been found in some nonthyroid cancers. However, it is mostly accumulated in the cytoplasm, and its functionality has not been demonstrated. We have investigated sodium iodide symporter expression and functionality in human liver cancer, and in a diethylnitrosamine induced Wistar rat model of primary liver cancer at different stages of carcinogenesis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0016-5085
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pubmed:author |
pubmed-author:Bioulac-SagePauletteP,
pubmed-author:BoisgardRaphaëlR,
pubmed-author:BréchotChristianC,
pubmed-author:CalèsPaulP,
pubmed-author:ClercJérômeJ,
pubmed-author:FaivreJamilaJ,
pubmed-author:GuettierCatherineC,
pubmed-author:HervéJulieJ,
pubmed-author:LiuBingkaiB,
pubmed-author:RouxJérômeJ,
pubmed-author:SamuelDidierD,
pubmed-author:TavitianBertrandB,
pubmed-author:ValogneYannickY,
pubmed-author:YilmazFundaF
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pubmed:issnType |
Print
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pubmed:volume |
132
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1495-503
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pubmed:meshHeading |
pubmed-meshheading:17408651-Animals,
pubmed-meshheading:17408651-Autoradiography,
pubmed-meshheading:17408651-Bile Duct Neoplasms,
pubmed-meshheading:17408651-Bile Ducts, Intrahepatic,
pubmed-meshheading:17408651-Carcinoma, Hepatocellular,
pubmed-meshheading:17408651-Cholangiocarcinoma,
pubmed-meshheading:17408651-Disease Progression,
pubmed-meshheading:17408651-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:17408651-Humans,
pubmed-meshheading:17408651-Immunoblotting,
pubmed-meshheading:17408651-Immunohistochemistry,
pubmed-meshheading:17408651-In Situ Nick-End Labeling,
pubmed-meshheading:17408651-Iodine,
pubmed-meshheading:17408651-Liver Neoplasms,
pubmed-meshheading:17408651-Liver Neoplasms, Experimental,
pubmed-meshheading:17408651-Male,
pubmed-meshheading:17408651-RNA, Messenger,
pubmed-meshheading:17408651-Rats,
pubmed-meshheading:17408651-Rats, Wistar,
pubmed-meshheading:17408651-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17408651-Symporters,
pubmed-meshheading:17408651-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:17408651-Tomography, X-Ray Computed
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pubmed:year |
2007
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pubmed:articleTitle |
Sodium iodide symporter is expressed at the preneoplastic stages of liver carcinogenesis and in human cholangiocarcinoma.
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pubmed:affiliation |
INSERM, U785, Centre Hépatobiliaire, Villejuif, France; Université Paris-Sud, Faculté de médecine, Villejuif, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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