17408632

Source:http://linkedlifedata.com/resource/pubmed/id/17408632

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0015127, umls-concept:C0015283, umls-concept:C0031715, umls-concept:C0256371, umls-concept:C0935597, umls-concept:C1314792, umls-concept:C1420508
pubmed:issue	4
pubmed:dateCreated	2007-4-30
pubmed:abstractText	Acute or chronic alcohol treatment does little to the exocrine pancreas but predisposes the pancreas to postprandial cholinergic stimulation that triggers cellular events leading to pancreatitis. This alcohol-induced susceptibility mechanism of pancreatitis is unknown.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R21 AA015579-01A1
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0374630
pubmed:citationSubset	AIM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Amylases, http://linkedlifedata.com/resource/pubmed/chemical/Carbachol, http://linkedlifedata.com/resource/pubmed/chemical/Cholinergic Agonists, http://linkedlifedata.com/resource/pubmed/chemical/DNA, http://linkedlifedata.com/resource/pubmed/chemical/Ethanol, http://linkedlifedata.com/resource/pubmed/chemical/FM1 43, http://linkedlifedata.com/resource/pubmed/chemical/Fluorescent Dyes, http://linkedlifedata.com/resource/pubmed/chemical/Munc18 Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Peroxidase, http://linkedlifedata.com/resource/pubmed/chemical/Protein Kinase C-alpha, http://linkedlifedata.com/resource/pubmed/chemical/Pyridinium Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Quaternary Ammonium Compounds, http://linkedlifedata.com/resource/pubmed/chemical/Solvents
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0016-5085
pubmed:author	pubmed-author:BinkerMarcelo GMG, pubmed-author:Cosen-BinkerLaura ILI, pubmed-author:GaisanoHerbert YHY, pubmed-author:LamPatrick P LPP
pubmed:issnType	Print
pubmed:volume	132
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1527-45
pubmed:dateRevised	2009-11-19
pubmed:meshHeading	pubmed-meshheading:17408632-Amylases, pubmed-meshheading:17408632-Animals, pubmed-meshheading:17408632-Carbachol, pubmed-meshheading:17408632-Cholinergic Agonists, pubmed-meshheading:17408632-DNA, pubmed-meshheading:17408632-Ethanol, pubmed-meshheading:17408632-Exocytosis, pubmed-meshheading:17408632-Fluorescent Dyes, pubmed-meshheading:17408632-Gene Expression, pubmed-meshheading:17408632-Immunoblotting, pubmed-meshheading:17408632-Immunoprecipitation, pubmed-meshheading:17408632-Male, pubmed-meshheading:17408632-Microscopy, Confocal, pubmed-meshheading:17408632-Microscopy, Electron, pubmed-meshheading:17408632-Munc18 Proteins, pubmed-meshheading:17408632-Pancreas, pubmed-meshheading:17408632-Pancreatitis, Alcoholic, pubmed-meshheading:17408632-Peroxidase, pubmed-meshheading:17408632-Phosphorylation, pubmed-meshheading:17408632-Protein Kinase C-alpha, pubmed-meshheading:17408632-Pyridinium Compounds, pubmed-meshheading:17408632-Quaternary Ammonium Compounds, pubmed-meshheading:17408632-Rats, pubmed-meshheading:17408632-Rats, Wistar, pubmed-meshheading:17408632-Solvents, pubmed-meshheading:17408632-Translocation, Genetic
pubmed:year	2007
pubmed:articleTitle	Alcohol-induced protein kinase Calpha phosphorylation of Munc18c in carbachol-stimulated acini causes basolateral exocytosis.
pubmed:affiliation	Department of Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural