rdf:type |
|
lifeskim:mentions |
umls-concept:C0008377,
umls-concept:C0009247,
umls-concept:C0010068,
umls-concept:C0011849,
umls-concept:C0021467,
umls-concept:C0021469,
umls-concept:C0023981,
umls-concept:C0030705,
umls-concept:C0032893,
umls-concept:C0205210,
umls-concept:C1532737,
umls-concept:C1554184,
umls-concept:C1964257
|
pubmed:issue |
4
|
pubmed:dateCreated |
2007-4-4
|
pubmed:abstractText |
Patients with primary hypercholesterolaemia and concomitant coronary heart disease (CHD) and/or diabetes mellitus (DM), who are at particularly high risk of cardiovascular events such as stroke or myocardial infarction, benefit from aggressive lipid lowering strategies. The present studies investigated the incremental efficacy and safety of dual cholesterol inhibition with ezetimibe/simvastatin in such high-risk patients pre-treated with statins but not reaching the 100 mg/dL (2.6 mmol/L) low density cholesterol (LDL-C) cholesterol threshold in the primary care setting.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
1473-4877
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
23
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
713-9
|
pubmed:dateRevised |
2009-10-28
|
pubmed:meshHeading |
pubmed-meshheading:17407627-Aged,
pubmed-meshheading:17407627-Anticholesteremic Agents,
pubmed-meshheading:17407627-Azetidines,
pubmed-meshheading:17407627-Cohort Studies,
pubmed-meshheading:17407627-Coronary Disease,
pubmed-meshheading:17407627-Diabetes Complications,
pubmed-meshheading:17407627-Dose-Response Relationship, Drug,
pubmed-meshheading:17407627-Drug Combinations,
pubmed-meshheading:17407627-Female,
pubmed-meshheading:17407627-Humans,
pubmed-meshheading:17407627-Hypercholesterolemia,
pubmed-meshheading:17407627-Male,
pubmed-meshheading:17407627-Middle Aged,
pubmed-meshheading:17407627-Primary Health Care,
pubmed-meshheading:17407627-Simvastatin,
pubmed-meshheading:17407627-Treatment Outcome
|
pubmed:year |
2007
|
pubmed:articleTitle |
Dual cholesterol inhibition with ezetimibe/simvastatin in pre-treated hypercholesterolaemic patients with coronary heart disease or diabetes mellitus: prospective observational cohort studies in clinical practice.
|
pubmed:affiliation |
Essex pharma, Medical Department, Munich, Germany. steven.hildemann@essex.de
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Evaluation Studies
|