Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
2007-4-3
pubmed:abstractText
c-Met is a receptor tyrosine kinase involved in cell growth, invasion, metastases, and angiogenesis. In this study, we investigated the role of c-Met in melanoma biology using a novel small-molecule tyrosine kinase inhibitor SU11274 and small interfering (si) RNA against the receptor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2246-53
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:17404109-Amino Acid Sequence, pubmed-meshheading:17404109-Base Sequence, pubmed-meshheading:17404109-Cell Differentiation, pubmed-meshheading:17404109-Cell Line, Tumor, pubmed-meshheading:17404109-Fluorescent Antibody Technique, pubmed-meshheading:17404109-Hepatocyte Growth Factor, pubmed-meshheading:17404109-Humans, pubmed-meshheading:17404109-Immunohistochemistry, pubmed-meshheading:17404109-Indoles, pubmed-meshheading:17404109-Melanoma, pubmed-meshheading:17404109-Microphthalmia-Associated Transcription Factor, pubmed-meshheading:17404109-Molecular Sequence Data, pubmed-meshheading:17404109-Mutation, pubmed-meshheading:17404109-Piperazines, pubmed-meshheading:17404109-Polymerase Chain Reaction, pubmed-meshheading:17404109-Protein Kinase Inhibitors, pubmed-meshheading:17404109-Proto-Oncogene Proteins c-met, pubmed-meshheading:17404109-RNA, Small Interfering, pubmed-meshheading:17404109-Reactive Oxygen Species, pubmed-meshheading:17404109-Skin Neoplasms, pubmed-meshheading:17404109-Sulfonamides, pubmed-meshheading:17404109-Transfection
pubmed:year
2007
pubmed:articleTitle
c-Met is a potentially new therapeutic target for treatment of human melanoma.
pubmed:affiliation
Departments of Hematology/Oncology and Pathology, University of Chicago Medical Center, Chicago, Illinois 60607, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural