17404101

Source:http://linkedlifedata.com/resource/pubmed/id/17404101

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0027651, umls-concept:C0332835, umls-concept:C1511291, umls-concept:C1514300, umls-concept:C1522222
pubmed:issue	7
pubmed:dateCreated	2007-4-3
pubmed:abstractText	The use of genetically engineered mouse (GEM) models for preclinical testing of anticancer therapies is hampered by variable tumor latency, incomplete penetrance, and complicated breeding schemes. Here, we describe and validate a transplantation strategy that circumvents some of these difficulties.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/N01-CO-12400
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	1078-0432
pubmed:author	pubmed-author:AnverMiriam RMR, pubmed-author:BarrettJ CarlJC, pubmed-author:BonomiCarrie ACA, pubmed-author:BorgelSuzanne DSD, pubmed-author:CarterJohn PJP, pubmed-author:CherryJamesJ, pubmed-author:DengChuxia XCX, pubmed-author:GreenJeff EJE, pubmed-author:HollingsheadMelinda GMG, pubmed-author:HunterKent WKW, pubmed-author:HurstingStephen DSD, pubmed-author:LukesLuanneL, pubmed-author:MerlinoGlennG, pubmed-author:MunroeDavid JDJ, pubmed-author:NunezNomelí PNP, pubmed-author:QiaoWenhuiW, pubmed-author:RoblesAna IAI, pubmed-author:SteegPatricia SPS, pubmed-author:StotlerHowardH, pubmed-author:VarticovskiLyubaL, pubmed-author:WakefieldLalage MLM, pubmed-author:WuXiaolinX
pubmed:issnType	Print
pubmed:day	1
pubmed:volume	13
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	2168-77
pubmed:dateRevised	2007-12-3
pubmed:meshHeading	pubmed-meshheading:17404101-Animals, pubmed-meshheading:17404101-Cell Proliferation, pubmed-meshheading:17404101-Disease Models, Animal, pubmed-meshheading:17404101-Female, pubmed-meshheading:17404101-Gene Expression, pubmed-meshheading:17404101-Gene Expression Profiling, pubmed-meshheading:17404101-Genetic Engineering, pubmed-meshheading:17404101-In Situ Hybridization, pubmed-meshheading:17404101-Mammary Neoplasms, Experimental, pubmed-meshheading:17404101-Mice, pubmed-meshheading:17404101-Mice, Transgenic, pubmed-meshheading:17404101-Neoplasm Metastasis, pubmed-meshheading:17404101-Neoplasm Transplantation, pubmed-meshheading:17404101-Oligonucleotide Array Sequence Analysis, pubmed-meshheading:17404101-Reverse Transcriptase Polymerase Chain Reaction
pubmed:year	2007
pubmed:articleTitle	Accelerated preclinical testing using transplanted tumors from genetically engineered mouse breast cancer models.
pubmed:affiliation	Center for Cancer Research, National Cancer Institute, Frederick, Maryland. varticol@mail.nih.gov
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural, Research Support, N.I.H., Intramural