Source:http://linkedlifedata.com/resource/pubmed/id/17400498
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
2007-8-6
|
| pubmed:abstractText |
Biallelic ablation of VGF determines a dwarf phenotype. VGF precursor protein encodes for different biologically active peptides none of which has been related to growth or muscular abnormalities. Here we present the first attempt to fill this gap. We tested the hypothesis that a recently identified VGF-derived peptide, TLQP-21, shown to centrally modulate metabolic functions, could also modulate growth hormone (GH)-axis and muscle strength.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Aug
|
| pubmed:issn |
1096-6374
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
17
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
342-5
|
| pubmed:meshHeading |
pubmed-meshheading:17400498-Animals,
pubmed-meshheading:17400498-Body Weight,
pubmed-meshheading:17400498-Growth Hormone,
pubmed-meshheading:17400498-Injections, Intraventricular,
pubmed-meshheading:17400498-Insulin-Like Growth Factor I,
pubmed-meshheading:17400498-Male,
pubmed-meshheading:17400498-Mice,
pubmed-meshheading:17400498-Muscle, Skeletal,
pubmed-meshheading:17400498-Muscle Strength,
pubmed-meshheading:17400498-Organ Size,
pubmed-meshheading:17400498-Peptide Fragments
|
| pubmed:year |
2007
|
| pubmed:articleTitle |
Chronic intracerebroventricular TLQP-21 delivery does not modulate the GH/IGF-1-axis and muscle strength in mice.
|
| pubmed:affiliation |
Institute of Neuroscience, CNR, Rome, Italy. bartolomucci@biol.unipr.it
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|