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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-7-9
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pubmed:abstractText |
U19/EAF2 is a potential tumor suppressor exhibiting frequent down-regulation and allelic loss in advanced human prostate cancer specimens. U19/EAF2 has also been identified as ELL-associated factor 2 (EAF2) based on its binding to ELL, a fusion partner of MLL in acute myeloid leukemia. U19/EAF2 is a putative transcription factor with a transactivation domain and capability of sequence-specific DNA binding.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-10086727,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-10644725,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-10933599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-11118326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-11238904,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-11418481,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-11463392,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-11566436,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-11606057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-12446457,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-12686606,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-12761297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-12841360,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-12907652,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-14517999,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-16006523,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-16114057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-16229834,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-7991593,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-8596958,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17395368-9371789
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Basic Helix-Loop-Helix...,
http://linkedlifedata.com/resource/pubmed/chemical/EAF1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/EAF2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/ELL protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/TFPT protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Transcription Factors,
http://linkedlifedata.com/resource/pubmed/chemical/Transcriptional Elongation Factors
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0304-3835
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
253
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
265-72
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pubmed:dateRevised |
2010-12-3
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pubmed:meshHeading |
pubmed-meshheading:17395368-Animals,
pubmed-meshheading:17395368-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:17395368-COS Cells,
pubmed-meshheading:17395368-Cercopithecus aethiops,
pubmed-meshheading:17395368-Humans,
pubmed-meshheading:17395368-Immunoprecipitation,
pubmed-meshheading:17395368-Transcription, Genetic,
pubmed-meshheading:17395368-Transcription Factors,
pubmed-meshheading:17395368-Transcriptional Elongation Factors,
pubmed-meshheading:17395368-Two-Hybrid System Techniques
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pubmed:year |
2007
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pubmed:articleTitle |
FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity.
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pubmed:affiliation |
Department of Urology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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