Linked Life Data

17395093

Source:http://linkedlifedata.com/resource/pubmed/id/17395093

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7-8
pubmed:dateCreated
2007-3-30
pubmed:abstractText
The costs for the development of new drugs have increased dramatically over the past 30 years. One of the main reasons for this increase is the low success rate of new drugs being approved for patient use, which is, in part, a consequence of the common use of rodent models for preclinical validation of efficacy. Especially in the development of biologicals, which are now successfully used in the treatment of rheumatoid arthritis, the selection of the right animal model is pivotal. Non-human primates could help to bridge the evolutionary gap between rodent models and human patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1359-6446
pubmed:author
pubmed:issnType
Print
pubmed:volume
12
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-35
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Preclinical models of arthritic disease in non-human primates.
pubmed:affiliation
Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands.
pubmed:publicationType
Journal Article, Review