Source:http://linkedlifedata.com/resource/pubmed/id/17393308
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
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pubmed:dateCreated |
2007-6-4
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pubmed:abstractText |
Unexplained chest/epigastric pain is a common symptom in the general population. However, it has not previously been studied whether such pain could be a marker of subsequent gastrointestinal cancer. We aimed to estimate the risk of gastrointestinal cancers in a Danish 10-year follow-up study among patients with chest/epigastric pain, normal upper endoscopy, and no prior discharge diagnosis of ischemic heart disease (N = 386), compared with population controls (N = 3860). The overall 10-year risk of gastrointestinal cancer (stomach, colorectal, liver, and pancreas) was 2.9% for patients with unexplained chest/epigastric pain vs. 1.5% for controls. The adjusted relative risks <1 year and > or =1 year after upper endoscopy were 8.4 (95% confidence interval [CI], 2.6-27.5) and 1.2 (95% CI, 0.5-2.9), respectively. We found that patients with unexplained chest/epigastric pain have an increased risk of gastrointestinal cancer within the first year after upper endoscopy. Consequently, unexplained chest/epigastric pain might be an early gastrointestinal cancer symptom.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0163-2116
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1730-7
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pubmed:meshHeading |
pubmed-meshheading:17393308-Adult,
pubmed-meshheading:17393308-Case-Control Studies,
pubmed-meshheading:17393308-Chest Pain,
pubmed-meshheading:17393308-Denmark,
pubmed-meshheading:17393308-Endoscopy, Digestive System,
pubmed-meshheading:17393308-Female,
pubmed-meshheading:17393308-Follow-Up Studies,
pubmed-meshheading:17393308-Gastrointestinal Neoplasms,
pubmed-meshheading:17393308-Humans,
pubmed-meshheading:17393308-Male,
pubmed-meshheading:17393308-Middle Aged,
pubmed-meshheading:17393308-Risk Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Risk of gastrointestinal cancer in patients with unexplained chest/epigastric pain and normal upper endoscopy: a Danish 10-year follow-up study.
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pubmed:affiliation |
Department of Clinical Epidemiology, Aarhus and Aalborg Hospital, Aarhus University Hospital, DK-8000, Aarhus, Denmark. emm@dce.au.dk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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