Linked Life Data

17393292

Source:http://linkedlifedata.com/resource/pubmed/id/17393292

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-5-23
pubmed:abstractText
Spike-timing-dependent plasticity (STDP) with asymmetric learning windows is commonly found in the brain and useful for a variety of spike-based computations such as input filtering and associative memory. A natural consequence of STDP is establishment of causality in the sense that a neuron learns to fire with a lag after specific presynaptic neurons have fired. The effect of STDP on synchrony is elusive because spike synchrony implies unitary spike events of different neurons rather than a causal delayed relationship between neurons. We explore how synchrony can be facilitated by STDP in oscillator networks with a pacemaker. We show that STDP with asymmetric learning windows leads to self-organization of feedforward networks starting from the pacemaker. As a result, STDP drastically facilitates frequency synchrony. Even though differences in spike times are lessened as a result of synaptic plasticity, the finite time lag remains so that perfect spike synchrony is not realized. In contrast to traditional mechanisms of large-scale synchrony based on mutual interaction of coupled neurons, the route to synchrony discovered here is enslavement of downstream neurons by upstream ones. Facilitation of such feedforward synchrony does not occur for STDP with symmetric learning windows.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0929-5313
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
327-45
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Formation of feedforward networks and frequency synchrony by spike-timing-dependent plasticity.
pubmed:affiliation
Amari Research Unit, RIKEN Brain Science Institute, 2-1 Hirosawa, Wako, Saitama, Japan. masuda@mist.i.u-tokyo.ac.jp
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't