Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2007-5-14
pubmed:abstractText
A retrospective review of cases histologically diagnosed as malignant lesions of the orofacial region in 1992-2003 from the records of the Department of Oral Pathology and Biology, Lagos University Teaching Hospital, Nigeria was carried out. All cases were subjected to analysis of age, gender, site distribution and histologic types. Malignant tumours constituted 18% of all the biopsies of orofacial lesions seen within the period. The mean age of patients was 42.2+/-21.5 years (range: 2.5-85). There were 177 (69%) epithelial tumours of which squamous cell carcinoma was predominant, 47 (18%) sarcomas and 32 (13%) lymphomas. Squamous cell carcinoma (44%) was the most common malignant orofacial tumour. Osteosarcoma (32%) and Burkitt's lymphoma (56%) was the predominant sarcoma and lymphoma, respectively. Patients with a histologic diagnosis of carcinoma were older than those with sarcomas and lymphomas (P<0.01), and those with a histologic diagnosis of malignant lymphoma were significantly younger than those with sarcomas (P<0.01). Almost 25% of patients with carcinomas were below the age of 40 years. Malignant orofacial tumours are not uncommon in the studied environment, with a sizable proportion of carcinomas occurring before the age of 40 years.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0901-5027
pubmed:author
pubmed:issnType
Print
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
403-8
pubmed:meshHeading
pubmed-meshheading:17391919-Adolescent, pubmed-meshheading:17391919-Adult, pubmed-meshheading:17391919-Age Factors, pubmed-meshheading:17391919-Aged, pubmed-meshheading:17391919-Aged, 80 and over, pubmed-meshheading:17391919-Burkitt Lymphoma, pubmed-meshheading:17391919-Carcinoma, pubmed-meshheading:17391919-Carcinoma, Squamous Cell, pubmed-meshheading:17391919-Child, pubmed-meshheading:17391919-Child, Preschool, pubmed-meshheading:17391919-Facial Neoplasms, pubmed-meshheading:17391919-Female, pubmed-meshheading:17391919-Humans, pubmed-meshheading:17391919-Lymphoma, pubmed-meshheading:17391919-Male, pubmed-meshheading:17391919-Mandibular Neoplasms, pubmed-meshheading:17391919-Maxillary Neoplasms, pubmed-meshheading:17391919-Middle Aged, pubmed-meshheading:17391919-Mouth Neoplasms, pubmed-meshheading:17391919-Nigeria, pubmed-meshheading:17391919-Osteosarcoma, pubmed-meshheading:17391919-Retrospective Studies, pubmed-meshheading:17391919-Sarcoma, pubmed-meshheading:17391919-Sex Factors
pubmed:year
2007
pubmed:articleTitle
Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital.
pubmed:affiliation
Department of Oral Pathology and Biology, College of Medicine, University of Lagos, Lagos, Nigeria.
pubmed:publicationType
Journal Article