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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2007-3-28
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pubmed:abstractText |
The accumulation of macrophages is known to be involved in the pathogenesis of age-related macular degeneration (AMD), but the reasons why macrophages accumulate in AMD lesions have not been determined. Because the histopathology of AMD has some factors common with those of atherosclerosis, the authors hypothesized that macrophages accumulate to take up oxidized lipoproteins in the eyes of patients with AMD, as has been demonstrated in atherosclerosis.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/CD68 antigen, human,
http://linkedlifedata.com/resource/pubmed/chemical/CXCL16 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CXC,
http://linkedlifedata.com/resource/pubmed/chemical/Keratins,
http://linkedlifedata.com/resource/pubmed/chemical/Lipoproteins, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/OLR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Scavenger,
http://linkedlifedata.com/resource/pubmed/chemical/Scavenger Receptors, Class E,
http://linkedlifedata.com/resource/pubmed/chemical/oxidized low density lipoprotein,
http://linkedlifedata.com/resource/pubmed/chemical/von Willebrand Factor
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0146-0404
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pubmed:author |
pubmed-author:ItabeHiroyukiH,
pubmed-author:KameiMotohiroM,
pubmed-author:KinoshitaShigeruS,
pubmed-author:KitaToruT,
pubmed-author:KumeNoriakiN,
pubmed-author:MatsudaKen-IchiK,
pubmed-author:MinamiManabuM,
pubmed-author:ShimaokaTakeshiT,
pubmed-author:SuzukiMihokoM,
pubmed-author:YonedaKazuhitoK,
pubmed-author:YoneharaShinS
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pubmed:issnType |
Print
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pubmed:volume |
48
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1801-7
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pubmed:meshHeading |
pubmed-meshheading:17389514-Aged,
pubmed-meshheading:17389514-Aged, 80 and over,
pubmed-meshheading:17389514-Antigens, CD,
pubmed-meshheading:17389514-Antigens, Differentiation, Myelomonocytic,
pubmed-meshheading:17389514-Chemokines, CXC,
pubmed-meshheading:17389514-Choroidal Neovascularization,
pubmed-meshheading:17389514-Female,
pubmed-meshheading:17389514-Humans,
pubmed-meshheading:17389514-Immunoenzyme Techniques,
pubmed-meshheading:17389514-Keratins,
pubmed-meshheading:17389514-Lipoproteins, LDL,
pubmed-meshheading:17389514-Macrophages,
pubmed-meshheading:17389514-Macular Degeneration,
pubmed-meshheading:17389514-Male,
pubmed-meshheading:17389514-Middle Aged,
pubmed-meshheading:17389514-Pigment Epithelium of Eye,
pubmed-meshheading:17389514-RNA, Messenger,
pubmed-meshheading:17389514-Receptors, Scavenger,
pubmed-meshheading:17389514-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17389514-Scavenger Receptors, Class E,
pubmed-meshheading:17389514-von Willebrand Factor
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pubmed:year |
2007
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pubmed:articleTitle |
Scavenger receptors for oxidized lipoprotein in age-related macular degeneration.
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pubmed:affiliation |
Department of Ophthalmology, Graduate School of Medicine, Osaka University, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. mkamei@ophthal.med.osaka-u.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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