Source:http://linkedlifedata.com/resource/pubmed/id/17384730
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
11
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pubmed:dateCreated |
2007-3-26
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pubmed:abstractText |
We describe a novel method for localizing a fluorescent inclusion in a homogeneous turbid medium through the use of time-resolved techniques. Based on the calculation of the mean time of the fluorescence curves, the method does not require a priori knowledge of either the fluorescence lifetime or the mean time of the instrument response function since it adopts a differential processing approach. Theoretical expressions were validated and experiments for assessing the accuracy of localization were carried out on liquid optical phantoms with a small fluorescent inclusion. The illumination and detection optical fibers were immersed in the medium to achieve infinite medium geometry as required by the model used. The experimental setup consisted of a time-correlated single-photon counting system. Submillimeter accuracy was achieved for the localization of the inclusion.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0003-6935
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
10
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2131-7
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pubmed:meshHeading |
pubmed-meshheading:17384730-Image Interpretation, Computer-Assisted,
pubmed-meshheading:17384730-Microscopy, Fluorescence,
pubmed-meshheading:17384730-Nanoparticles,
pubmed-meshheading:17384730-Nephelometry and Turbidimetry,
pubmed-meshheading:17384730-Particle Size,
pubmed-meshheading:17384730-Phantoms, Imaging
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pubmed:year |
2007
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pubmed:articleTitle |
Analytical method for localizing a fluorescent inclusion in a turbid medium.
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pubmed:affiliation |
Département micro Technologies pour la Biologie et la Santé, CEA-LETI Recherche Technologique Grenoble, Grenoble, France. aurelie.laidevant@wanadoo.fr
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pubmed:publicationType |
Journal Article,
Evaluation Studies
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