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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-3-26
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pubmed:abstractText |
Type 2 deiodinase plays a critical role in thyroid hormone homeostasis. A single nucleotide polymorphism in DIO2 gene (A/G) in humans has been associated with a approximately 20% lower glucose disposal rate and greater insulin resistance in type 2 diabetes (DM2) patients.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1050-7256
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
199-202
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17381351-Adult,
pubmed-meshheading:17381351-Blood Glucose,
pubmed-meshheading:17381351-Diabetes Mellitus, Type 2,
pubmed-meshheading:17381351-Female,
pubmed-meshheading:17381351-Gene Frequency,
pubmed-meshheading:17381351-Humans,
pubmed-meshheading:17381351-Insulin Resistance,
pubmed-meshheading:17381351-Iodide Peroxidase,
pubmed-meshheading:17381351-Male,
pubmed-meshheading:17381351-Middle Aged,
pubmed-meshheading:17381351-Polymorphism, Genetic,
pubmed-meshheading:17381351-Proportional Hazards Models,
pubmed-meshheading:17381351-Regression Analysis,
pubmed-meshheading:17381351-Risk Factors,
pubmed-meshheading:17381351-Sequence Analysis, DNA
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pubmed:year |
2007
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pubmed:articleTitle |
The type 2 deiodinase (DIO2) A/G polymorphism is not associated with glycemic traits: the Framingham Heart Study.
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pubmed:affiliation |
Endocrine Division, Hospital de Clínicas de Porto Alegre, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil. almaia@ufrgs.br
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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