| pubmed-article:17377810 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:17377810 | lifeskim:mentions | umls-concept:C1123023 | lld:lifeskim |
| pubmed-article:17377810 | lifeskim:mentions | umls-concept:C0011306 | lld:lifeskim |
| pubmed-article:17377810 | lifeskim:mentions | umls-concept:C0205332 | lld:lifeskim |
| pubmed-article:17377810 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:17377810 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:17377810 | pubmed:dateCreated | 2007-3-22 | lld:pubmed |
| pubmed-article:17377810 | pubmed:abstractText | Distinguishing between low-grade primary cutaneous B-cell lymphoma (LG-pCBCL) and cutaneous lymphoid hyperplasia (CLH) based on histological features is often difficult. CLH lesions contain numerous reactive cells of the histiocyte lineage [Langerhans cells (LC), dermal dendritic cells (DDC), and macrophages], which are also often present in CBCL. The aim of this study was to determine whether immunohistochemical detection of those cells could help differentiate between CLH and LG-pCBCL. We determined the percentages of those histiocytic cells in the dermal infiltrates of 45 cases of cutaneous lymphoproliferations comprising 16 CLH and 29 LG-pCBCL (19 follicle-center cell lymphomas and 10 marginal zone lymphomas) by immunohistochemical labeling with antibodies to CD1a, FXIIIa, and CD68 to respectively detect LC, DDC, and macrophages. To avoid observer-dependent bias, an automated morphometric analysis method was used to recognize immunoreactive cells and calculate their percentages within the infiltrate. FXIIIa(+) cells were significatively more frequent in CLH than in LG-pCBCL, whereas CD1a(+) and CD68(+) cell frequencies were comparable in the two groups. The results of our study suggest that DDC might play an important role in the genesis of cutaneous lymphomas. | lld:pubmed |
| pubmed-article:17377810 | pubmed:language | eng | lld:pubmed |
| pubmed-article:17377810 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:17377810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:17377810 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:17377810 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:17377810 | pubmed:issn | 0945-6317 | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:Molinier-Fren... | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:LarocheLilian... | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:Martin-Garcia... | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:BagotMartineM | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:OrtonneNicola... | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:WechslerJanin... | lld:pubmed |
| pubmed-article:17377810 | pubmed:author | pubmed-author:CarbonnelleAm... | lld:pubmed |
| pubmed-article:17377810 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:17377810 | pubmed:volume | 450 | lld:pubmed |
| pubmed-article:17377810 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:17377810 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:17377810 | pubmed:pagination | 441-7 | lld:pubmed |
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| pubmed-article:17377810 | pubmed:meshHeading | pubmed-meshheading:17377810... | lld:pubmed |
| pubmed-article:17377810 | pubmed:year | 2007 | lld:pubmed |
| pubmed-article:17377810 | pubmed:articleTitle | Study of the reactive dendritic cells in small B-cell lymphoproliferations of the skin. | lld:pubmed |
| pubmed-article:17377810 | pubmed:affiliation | Département de Pathologie, Hôpital Henri Mondor, VI AP-HP, Université Paris XII, Créteil, France. | lld:pubmed |
| pubmed-article:17377810 | pubmed:publicationType | Journal Article | lld:pubmed |
