Source:http://linkedlifedata.com/resource/pubmed/id/17373325
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-3-21
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pubmed:abstractText |
Because upper respiratory tract infections, particularly tonsillitis, often precede IgA nephropathy (IgAN), IgAN is now recognized as a tonsil-related disease, and reports have shown that tonsillectomy is effective in preventing disease progression in IgAN patients. IgA may thus play an important role in IgAN pathogenesis and development. B cell activation factor belonging to the TNF family (BAFF) is expressed by monocytes, macrophages, and dendritic cells, and may be the mechanism by which macrophages and dendritic cells directly regulate human B-cell activation. BAFF acts as a potent B-cell growth factor and costimulator of immunoglobulin production, including IgA. We studied therapeutic effects and serum BAFF levels as prognostic factors.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0030-6622
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
110
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
53-9
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pubmed:dateRevised |
2011-7-28
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pubmed:meshHeading |
pubmed-meshheading:17373325-Adolescent,
pubmed-meshheading:17373325-Adult,
pubmed-meshheading:17373325-Aged,
pubmed-meshheading:17373325-B-Cell Activating Factor,
pubmed-meshheading:17373325-Disease Progression,
pubmed-meshheading:17373325-Female,
pubmed-meshheading:17373325-Glomerulonephritis, IGA,
pubmed-meshheading:17373325-Humans,
pubmed-meshheading:17373325-Male,
pubmed-meshheading:17373325-Middle Aged,
pubmed-meshheading:17373325-Prognosis,
pubmed-meshheading:17373325-Tonsillectomy
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pubmed:year |
2007
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pubmed:articleTitle |
[Therapeutic effects and prognostic factors in tonsillectomy patients with IgA nephropathy].
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pubmed:affiliation |
Department of Otolaryngology, Head and Neck Surgery, Asahikawa Medical School, Asahikawa.
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pubmed:publicationType |
Journal Article,
English Abstract
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