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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-3-20
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pubmed:abstractText |
Radiolabeled Annexin V-derivatives are well characterized phosphatidylserine-targeting biomarkers and considered as state-of-the-art tracers for non-invasive molecular imaging of apoptosis. In contrast to Annexin V-derived imaging agents being surrogate markers of apoptosis, activated cysteinyl aspartate-specific proteases (caspases) represent the common final path of apoptosis being a suitable in vivo target for the exclusive imaging of apoptotic tissues in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1824-4785
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
51
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
67-73
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pubmed:meshHeading |
pubmed-meshheading:17372575-Animals,
pubmed-meshheading:17372575-Apoptosis,
pubmed-meshheading:17372575-Caspases,
pubmed-meshheading:17372575-Isatin,
pubmed-meshheading:17372575-Isotope Labeling,
pubmed-meshheading:17372575-Mice,
pubmed-meshheading:17372575-Mice, Nude,
pubmed-meshheading:17372575-Positron-Emission Tomography,
pubmed-meshheading:17372575-Pyrrolidines,
pubmed-meshheading:17372575-Radiopharmaceuticals
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pubmed:year |
2007
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pubmed:articleTitle |
The nonpeptidyl caspase binding radioligand (S)-1-(4-(2-[18F]Fluoroethoxy)-benzyl)-5-[1-(2-methoxymethylpyrrolidinyl)sulfonyl]isatin ([18F]CbR) as potential positron emission tomography-compatible apoptosis imaging agent.
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pubmed:affiliation |
Department of Nuclear Medicine, University Hospital Muenster, Muenster, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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