Source:http://linkedlifedata.com/resource/pubmed/id/17370243
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
8
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pubmed:dateCreated |
2007-5-10
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pubmed:abstractText |
(-)-Cytisine and its derivatives are promising alkaloids in the development of new drugs for the treatment of disorders of the central nervous system (CNS). Electron ionization (EI) mass spectral fragmentations of cytisine (1), N-methylcytisine (2), N-ethylcytisine (3), N-acetylcytisine (4), N-propionylcytisine (5) and N-benzoylcytisine (6) have been investigated. Detailed fragmentation pathways have been identified for all significant ions, including a few characteristic fragment ions. The principal fragmentation routes of compounds 1-6 have been determined on the basis of EI low-resolution, high-resolution and B2/E linked scans as well as linked scans at constant B/E.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Alkaloids,
http://linkedlifedata.com/resource/pubmed/chemical/Amides,
http://linkedlifedata.com/resource/pubmed/chemical/Azocines,
http://linkedlifedata.com/resource/pubmed/chemical/N-methylcytisine,
http://linkedlifedata.com/resource/pubmed/chemical/Quinolizines,
http://linkedlifedata.com/resource/pubmed/chemical/cytisine
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pubmed:status |
MEDLINE
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pubmed:issn |
0951-4198
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pubmed:author | |
pubmed:copyrightInfo |
Copyright (c) 2007 John Wiley & Sons, Ltd.
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pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1409-13
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pubmed:meshHeading |
pubmed-meshheading:17370243-Alkaloids,
pubmed-meshheading:17370243-Alkylation,
pubmed-meshheading:17370243-Amides,
pubmed-meshheading:17370243-Amination,
pubmed-meshheading:17370243-Azocines,
pubmed-meshheading:17370243-Quinolizines,
pubmed-meshheading:17370243-Spectrometry, Mass, Electrospray Ionization
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pubmed:year |
2007
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pubmed:articleTitle |
Electron ionization mass spectral study of selected N-amide and N-alkyl derivatives of cytisine.
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pubmed:affiliation |
Faculty of Chemistry, A. Mickiewicz University, Grunwaldzka 6, 60-780 Pozna?, Poland. Anna.Przybyl@amu.edu.pl
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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