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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
9
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pubmed:dateCreated |
2007-3-19
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pubmed:abstractText |
Liver metastases represent the principal cause of death in patients with advanced colorectal cancer (CRC). Injection of resin microspheres (SIR Spheres)--containing the beta-emitter, yttrium-90--into the arterial supply of the liver can cause radioembolization of metastases. This treatment has not been tested with the radiosensitizing chemotherapy, oxaliplatin, which appears synergistic in the treatment of CRC when combined with fluorouracil and leucovorin (FOLFOX).
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1527-7755
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
20
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1099-106
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pubmed:meshHeading |
pubmed-meshheading:17369573-Adenocarcinoma,
pubmed-meshheading:17369573-Aged,
pubmed-meshheading:17369573-Antineoplastic Agents,
pubmed-meshheading:17369573-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:17369573-Australia,
pubmed-meshheading:17369573-Brachytherapy,
pubmed-meshheading:17369573-Chemotherapy, Adjuvant,
pubmed-meshheading:17369573-Colorectal Neoplasms,
pubmed-meshheading:17369573-Disease-Free Survival,
pubmed-meshheading:17369573-Embolization, Therapeutic,
pubmed-meshheading:17369573-Female,
pubmed-meshheading:17369573-Fluorouracil,
pubmed-meshheading:17369573-Great Britain,
pubmed-meshheading:17369573-Humans,
pubmed-meshheading:17369573-Leucovorin,
pubmed-meshheading:17369573-Liver Neoplasms,
pubmed-meshheading:17369573-Male,
pubmed-meshheading:17369573-Maximum Tolerated Dose,
pubmed-meshheading:17369573-Microspheres,
pubmed-meshheading:17369573-Middle Aged,
pubmed-meshheading:17369573-Organoplatinum Compounds,
pubmed-meshheading:17369573-Radiopharmaceuticals,
pubmed-meshheading:17369573-Radiotherapy, Adjuvant,
pubmed-meshheading:17369573-Time Factors,
pubmed-meshheading:17369573-Treatment Outcome,
pubmed-meshheading:17369573-Vitamin B Complex,
pubmed-meshheading:17369573-Yttrium Radioisotopes
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pubmed:year |
2007
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pubmed:articleTitle |
Radioembolization of liver metastases from colorectal cancer using yttrium-90 microspheres with concomitant systemic oxaliplatin, fluorouracil, and leucovorin chemotherapy.
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pubmed:affiliation |
Department of Radiation Oncology and Biology, University of Oxford, Churchill Hospital, Oxford, UK. ricky.sharma@rob.ox.ac.uk
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pubmed:publicationType |
Journal Article,
Multicenter Study,
Clinical Trial, Phase I
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