Source:http://linkedlifedata.com/resource/pubmed/id/17369042
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2007-4-30
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pubmed:abstractText |
Self-protecting Ti6Al4V alloy pins were prepared by covalent bonding of bis(ethylene glycol) linkers, then vancomycin to the oxidized, aminopropylated Ti6Al4V alloy surface. Fluorescence modification-enabled estimation of yields of free amines on the metallic surface monolayer at each reaction step. The vancomycin-protected Ti6Al4V pins were not colonized by Staphylococcus aureus, even after 44days storage in physiological buffer. These results provide a basis for testing self-protection against S. aureus colonization in animal models.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0960-894X
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pubmed:author |
pubmed-author:AdamsChristopher SCS,
pubmed-author:AntociValentinVJr,
pubmed-author:EdupugantiOm POP,
pubmed-author:HickokNoreen JNJ,
pubmed-author:JoseBinoyB,
pubmed-author:KingSamuel BSB,
pubmed-author:ParviziJavadJ,
pubmed-author:ShapiroIrving MIM,
pubmed-author:WickstromEricE,
pubmed-author:ZeigerAllen RAR
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
17
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2692-6
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pubmed:meshHeading | |
pubmed:year |
2007
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pubmed:articleTitle |
Covalent bonding of vancomycin to Ti6Al4V alloy pins provides long-term inhibition of Staphylococcus aureus colonization.
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pubmed:affiliation |
Department of Biochemistry & Molecular Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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