Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1992-3-9
pubmed:abstractText
Serial measurements of serum intact parathyroid hormone (PTH) and adjusted total calcium levels were performed on 10 patients during unilateral neck exploration for a solitary parathyroid adenoma localised preoperatively by ultrasound scan. Frozen section was performed peroperatively to establish the presence of parathyroid tissue. Levels of PTH were shown to be within the normal range within 15 min of adenoma removal (a mean of 13.4% of their preoperative values), allowing clear early distinction from unsuccessful surgery where no change occurred. Frozen section wrongly identified thyroid tissue as parathyroid in one case leading to a failure of the initial neck exploration. Our findings show that intraoperative PTH measurements can accurately predict whether all hyperfunctioning parathyroid tissue has been removed. This is not always possible using frozen section techniques. The wider use of intraoperative PTH measurement, particularly in difficult cases, may avoid the need for prolonged explorations to identify all four glands and, perhaps, biopsy of normal glands, replacing the current standard use of frozen section as a more reliable indicator of the success of parathyroid surgery.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-2310158, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-2317677, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-2757503, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-2814766, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-2919966, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3125129, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3130120, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3194839, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3254105, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3350905, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3608153, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3608156, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3624408, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3686358, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-3787460, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-5693024, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-6104128, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-6311857, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-7074331, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-7135203, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-898024, http://linkedlifedata.com/resource/pubmed/commentcorrection/1736788-961467
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0035-8843
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-22
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Intraoperative parathyroid hormone estimation: a valuable adjunct to parathyroid surgery.
pubmed:affiliation
Department of Surgery, Leicester Royal Infirmary.
pubmed:publicationType
Journal Article