Linked Life Data

17364063

Source:http://linkedlifedata.com/resource/pubmed/id/17364063

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2007-3-16
pubmed:abstractText
Passive behavior in the open field test and high anxiety in an elevated plus-maze develop in OXYS rats by the age of 3 months and are regarded as manifestations of early aging. We studied the possibility of preventing these disturbances with vitamin E and whortleberry extract (20 mg/kg for 45 days from the age of 1.5 months). Whortleberry extract alone increased horizontal activity and reduced anxiety of OXYS rats, while anxiety in Wistar rats increased significantly after treatment with both preparations, and especially with vitamin E: the number of entries into open arms of the elevated plus-maze and the time spent there decreased. The results necessitate comprehensive evaluation of the aftereffects of long-term use of antioxidants, acknowledged geroprotectors intended for preventive use.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0007-4888
pubmed:author
pubmed:issnType
Print
pubmed:volume
141
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
734-7
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Opposite effects of antioxidants on anxiety in Wistar and OXYS rats.
pubmed:affiliation
Institute of Cytology and Genetics, Siberian Division of Russian Academy of Sciences, Novosibirsk. kolosova@bionet.nsc.ru
pubmed:publicationType
Journal Article, Comparative Study, Research Support, Non-U.S. Gov't