rdf:type |
|
lifeskim:mentions |
umls-concept:C0026088,
umls-concept:C0034840,
umls-concept:C0042232,
umls-concept:C0087111,
umls-concept:C0205296,
umls-concept:C0332437,
umls-concept:C0392747,
umls-concept:C0443172,
umls-concept:C0456205,
umls-concept:C1136254,
umls-concept:C1522570,
umls-concept:C1550605
|
pubmed:issue |
4
|
pubmed:dateCreated |
2007-3-16
|
pubmed:abstractText |
We have previously shown that the antigestagen mifepristone is contraceptive when given in a daily dose of 5 mg, po. Epidemiological studies suggest that gestagen-only contraceptives may increase the risk of transmission of human immunodeficiency virus (HIV) due to effects on the vaginal defenses to infection. We investigate the effects of mifepristone on vaginal thickness, steroid receptor and natural antimicrobial content and pharmacokinetics of mifepristone.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anti-Infective Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Differentiation...,
http://linkedlifedata.com/resource/pubmed/chemical/Contraceptives, Oral, Synthetic,
http://linkedlifedata.com/resource/pubmed/chemical/Elafin,
http://linkedlifedata.com/resource/pubmed/chemical/GNLY protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Mifepristone,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Steroid,
http://linkedlifedata.com/resource/pubmed/chemical/Secretory Leukocyte Peptidase...,
http://linkedlifedata.com/resource/pubmed/chemical/beta-Defensins
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pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0010-7824
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pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
75
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
271-80
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pubmed:dateRevised |
2010-9-1
|
pubmed:meshHeading |
pubmed-meshheading:17362705-Adult,
pubmed-meshheading:17362705-Anti-Infective Agents,
pubmed-meshheading:17362705-Antigens, Differentiation, T-Lymphocyte,
pubmed-meshheading:17362705-Contraceptives, Oral, Synthetic,
pubmed-meshheading:17362705-Elafin,
pubmed-meshheading:17362705-Endometrium,
pubmed-meshheading:17362705-Female,
pubmed-meshheading:17362705-Gene Expression,
pubmed-meshheading:17362705-Humans,
pubmed-meshheading:17362705-Mifepristone,
pubmed-meshheading:17362705-Ovary,
pubmed-meshheading:17362705-Pilot Projects,
pubmed-meshheading:17362705-RNA, Messenger,
pubmed-meshheading:17362705-Receptors, Steroid,
pubmed-meshheading:17362705-Secretory Leukocyte Peptidase Inhibitor,
pubmed-meshheading:17362705-Vagina,
pubmed-meshheading:17362705-beta-Defensins
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pubmed:year |
2007
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pubmed:articleTitle |
Changes in vaginal morphology, steroid receptor and natural antimicrobial content following treatment with low-dose mifepristone.
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pubmed:affiliation |
Contraceptive Development Network, Centre for Reproductive Biology, University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, EH16 4TJ Edinburgh, UK.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
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