Linked Life Data

17361426

Source:http://linkedlifedata.com/resource/pubmed/id/17361426

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-7-10
pubmed:abstractText
Temporary immobilization of the leg serves as a useful model for the brain's adaptive responses to casting, long-term confinement to bed rest and possibly to trauma. As part of a larger program using TMS to investigate changes associated with bed rest, we sought to determine whether casting of the leg causes brain excitability changes measurable with TMS, and the time course of resolution of these changes. In this study, eight adults wore a full leg cast for 10 days. TMS measures of motor cortex excitability were gathered before the cast was placed, and then immediately after cast removal, and 24 and 48 h later. A control group did not wear a cast and underwent the same TMS sessions. Significant excitability changes occurred and peaked at 24 h post cast removal in the TMS experimental group but not the non-casted group.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0014-4819
pubmed:author
pubmed:issnType
Print
pubmed:volume
181
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
213-20
pubmed:dateRevised
2009-11-11
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Lower limb immobilization is associated with increased corticospinal excitability.
pubmed:affiliation
Brain Stimulation Laboratory (BSL), Institute of Psychiatry, Medical University of South Carolina, MUSC IOP, 502 N, 67 President Street, Charleston, SC 29425, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't