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pubmed-article:17356514pubmed:abstractTextLittle is known about the mechanisms that regulate cell cycle withdrawal of the retinal pigment epithelium (RPE) during development, or about the mechanisms maintaining epithelial cell quiescence in adult retinas. The present study examines the potential role of the negative cell cycle regulator p27(Kip1) in controlling RPE proliferation, using mice with targeted ablation of the p27(Kip1) gene.lld:pubmed
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pubmed-article:17356514pubmed:articleTitleDefects in retinal pigment epithelium cell proliferation and retinal attachment in mutant mice with p27(Kip1) gene ablation.lld:pubmed
pubmed-article:17356514pubmed:affiliationDepartment of Anatomy and Cell Biology, James H. Quillen College of Medicine, East Tennessee State University, Johnson City, TN 37614-0582, USA. defoe@etsu.edu <defoe@etsu.edu>lld:pubmed
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