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rdf:type |
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lifeskim:mentions |
umls-concept:C0004147,
umls-concept:C0011860,
umls-concept:C0014257,
umls-concept:C0020538,
umls-concept:C0030705,
umls-concept:C0126174,
umls-concept:C0242606,
umls-concept:C0332307,
umls-concept:C0542341,
umls-concept:C1280500,
umls-concept:C1707455
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pubmed:issue |
4
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pubmed:dateCreated |
2007-3-12
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pubmed:abstractText |
It has been shown that angiotensin-converting enzyme inhibition or angiotensin receptor blockade may improve endothelial dysfunction, an early manifestation of atherosclerosis, in patients with diabetes. Whether this protective effect is mediated through blood pressure-lowering effects or other specific mechanisms such as a reduction in oxidative stress is not clear. We investigated the influence of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0263-6352
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pubmed:author |
pubmed-author:ChenevardRémyR,
pubmed-author:FlammerAndreas JAJ,
pubmed-author:GaySteffenS,
pubmed-author:HürlimannDavidD,
pubmed-author:HermannFrankF,
pubmed-author:LüscherThomas FTF,
pubmed-author:LehmannRogerR,
pubmed-author:NeidhartMichelM,
pubmed-author:NollGeorgG,
pubmed-author:RiesenWalterW,
pubmed-author:RuschitzkaFrankF,
pubmed-author:SchweglerBeatB,
pubmed-author:SudanoIsabellaI,
pubmed-author:WiesliPeterP
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
785-91
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pubmed:meshHeading |
pubmed-meshheading:17351370-Antihypertensive Agents,
pubmed-meshheading:17351370-Atenolol,
pubmed-meshheading:17351370-Blood Pressure,
pubmed-meshheading:17351370-Brachial Artery,
pubmed-meshheading:17351370-Cross-Over Studies,
pubmed-meshheading:17351370-Diabetes Mellitus, Type 2,
pubmed-meshheading:17351370-Dinoprost,
pubmed-meshheading:17351370-Double-Blind Method,
pubmed-meshheading:17351370-Endothelium, Vascular,
pubmed-meshheading:17351370-Female,
pubmed-meshheading:17351370-Humans,
pubmed-meshheading:17351370-Hypertension,
pubmed-meshheading:17351370-Insulin Resistance,
pubmed-meshheading:17351370-Losartan,
pubmed-meshheading:17351370-Male,
pubmed-meshheading:17351370-Middle Aged,
pubmed-meshheading:17351370-Oxidative Stress,
pubmed-meshheading:17351370-Regional Blood Flow,
pubmed-meshheading:17351370-Research Design,
pubmed-meshheading:17351370-Treatment Outcome,
pubmed-meshheading:17351370-Vasodilation
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pubmed:year |
2007
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pubmed:articleTitle |
Effect of losartan, compared with atenolol, on endothelial function and oxidative stress in patients with type 2 diabetes and hypertension.
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pubmed:affiliation |
Cardiovascular Center, Cardiology, University Hospital Zurich, Switzerland.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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