Linked Life Data

17350840

Source:http://linkedlifedata.com/resource/pubmed/id/17350840

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2007-4-30
pubmed:abstractText
A collection of aryl sulfonamido indanes based on the lead compound 1 was synthesized and evaluated for Kv1.5 inhibitory activity. Kv1.5 inhibitors have the potential to be atrium-selective agents for treatment of atrial fibrillation. (1R,2R)-1 has an IC(50) of 0.033microM against Kv1.5 and is selective against other cardiac ion channels, including hERG.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0960-894X
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2849-53
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Aryl sulfonamido indane inhibitors of the Kv1.5 ion channel.
pubmed:affiliation
Icagen Inc., PO Box 14487, Research Triangle Park, NC 27709, USA.
pubmed:publicationType
Journal Article, Evaluation Studies