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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-4-19
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pubmed:abstractText |
Thrombus formation after atherosclerotic plaque rupture critically involves the platelet collagen receptor glycoprotein (GP) VI. We investigated the impact of EXP3179, an active metabolite of the angiotensin II type 1 (AT1)-receptor antagonist Losartan (LOS) on GPVI-dependent platelet activation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1524-4636
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pubmed:author |
pubmed-author:GawazMeinradM,
pubmed-author:GrothusenChristinaC,
pubmed-author:KonradIldikoI,
pubmed-author:KremmerElisabethE,
pubmed-author:LuchtefeldMarenM,
pubmed-author:MassbergSteffenS,
pubmed-author:SchiefferBernhardB,
pubmed-author:SchmidtBorisB,
pubmed-author:SchulzChristianC,
pubmed-author:StellosKonstantinosK,
pubmed-author:TeebkenOmkeO,
pubmed-author:UmbreenSumairaS
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pubmed:issnType |
Electronic
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1184-90
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pubmed:dateRevised |
2008-6-10
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pubmed:meshHeading |
pubmed-meshheading:17347483-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:17347483-Atherosclerosis,
pubmed-meshheading:17347483-Flow Cytometry,
pubmed-meshheading:17347483-Humans,
pubmed-meshheading:17347483-Losartan,
pubmed-meshheading:17347483-Microscopy, Fluorescence,
pubmed-meshheading:17347483-Platelet Aggregation,
pubmed-meshheading:17347483-Platelet Membrane Glycoproteins,
pubmed-meshheading:17347483-Receptor, Angiotensin, Type 1,
pubmed-meshheading:17347483-Thrombosis,
pubmed-meshheading:17347483-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
EXP3179 inhibits collagen-dependent platelet activation via glycoprotein receptor-VI independent of AT1-receptor antagonism: potential impact on atherothrombosis.
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pubmed:affiliation |
Abt. fuer Kardiologie und Angiologie, Medizinische Hochschule Hannover, Carl-Neuberg-Str. 1, 30625 Hannover, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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