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pubmed-article:17346963pubmed:abstractTextThe fungus Daedalea quercina (oak mazegill) was examined for its capability of producing antioxidative and anti-inflammatory compounds. Bioactivity guided fractionation of the extract from a mycelial culture led to the isolation of quercinol, which was identified as (-)-(2S)-2-hydroxymethyl-2-methyl-6-hydroxychromene 1 by NMR and X-ray analyses. The cryptic hydroquinone 1 shows a broad anti-inflammatory activity against cyclooxygenase 2 (COX-2), xanthine oxidase (XO), and horseradish peroxidase (HRP) at micromolar concentrations.lld:pubmed
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pubmed-article:17346963pubmed:articleTitleQuercinol, an anti-inflammatory chromene from the wood-rotting fungus Daedalea quercina (Oak Mazegill).lld:pubmed
pubmed-article:17346963pubmed:affiliationLeibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstr. 11a, 07745 Jena, Germany.lld:pubmed
pubmed-article:17346963pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17346963pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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