|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0006141,
umls-concept:C0011923,
umls-concept:C0024671,
umls-concept:C0029144,
umls-concept:C0043210,
umls-concept:C0221198,
umls-concept:C0449450,
umls-concept:C0449851,
umls-concept:C0522499,
umls-concept:C1518422,
umls-concept:C1548161,
umls-concept:C1707520,
umls-concept:C2607943,
umls-concept:C2926606
|
|
pubmed:dateCreated |
2007-3-6
|
|
pubmed:abstractText |
The purpose of this prospective study is to determine the diagnostic accuracy of near-infrared breast optical absorption imaging in patients with Breast Imaging Reporting and Data System (BIRADS) 4-5 non-palpable lesions scheduled for biopsy, using pathology after core or excisional biopsy as a reference. The patient's breast was positioned onto a panel of red light-emitting diodes (640 nm). A soft membrane was inflated to exert a uniform pressure on the breast. Transmitted light was detected using a CCD camera. The entire acquisition sequence took 1 minute. Image processing generated dynamic images displayed in colour scale, to reveal time-dependent changes in the transmitted light intensity caused by the pressure change. Dynamic curves were classified in two categories: consistently decreasing intensity suspicious for malignancy, and sinusoidal increasing intensity considered as benign. Seventy-eight women consulting for non-palpable breast lesions were initially included in the study. An imaging-histology correlation was obtained for seventy-two patients, the remaining six patients were excluded for technical optical scan reasons. We experienced an overall sensitivity of 73% and specificity of 38%, the false negative results being mainly small size (<10 mm) infiltrating malignant lesions and ductal carcinoma in situ (DCIS). False positive results were seen in benign proliferative lesions. Dynamic optical breast imaging is a novel, low-cost, non-invasive technique yielding a new type of information about the physiology of breast lesions. Absorption is due to haemoglobin and its products, therefore reflecting the angiogenic status of breast tumours.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-10933066,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-10938788,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-11152812,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-12490517,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-12790468,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-15128196,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-15797295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-15799826,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-15895597,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-16023382,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-16173820,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-16183924,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-16457705,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-17212539,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-2684393,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-6198502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17339139-9177241
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1470-7330
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
7
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
34-40
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:17339139-Absorption,
pubmed-meshheading:17339139-Adult,
pubmed-meshheading:17339139-Aged,
pubmed-meshheading:17339139-Breast Diseases,
pubmed-meshheading:17339139-Breast Neoplasms,
pubmed-meshheading:17339139-Calcinosis,
pubmed-meshheading:17339139-Carcinoma, Ductal, Breast,
pubmed-meshheading:17339139-Carcinoma, Intraductal, Noninfiltrating,
pubmed-meshheading:17339139-Diagnosis, Differential,
pubmed-meshheading:17339139-Equipment Design,
pubmed-meshheading:17339139-False Negative Reactions,
pubmed-meshheading:17339139-Female,
pubmed-meshheading:17339139-Hemoglobins,
pubmed-meshheading:17339139-Humans,
pubmed-meshheading:17339139-Middle Aged,
pubmed-meshheading:17339139-Neovascularization, Pathologic,
pubmed-meshheading:17339139-Palpation,
pubmed-meshheading:17339139-Prospective Studies,
pubmed-meshheading:17339139-Sensitivity and Specificity,
pubmed-meshheading:17339139-Severity of Illness Index,
pubmed-meshheading:17339139-Spectroscopy, Near-Infrared,
pubmed-meshheading:17339139-Transillumination
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Optical mammography: a new technique for visualizing breast lesions in women presenting non palpable BIRADS 4-5 imaging findings: preliminary results with radiologic-pathologic correlation.
|
|
pubmed:affiliation |
Institut Gustav Roussy, France.
|
|
pubmed:publicationType |
Journal Article,
Evaluation Studies
|
