rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2007-3-5
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pubmed:abstractText |
Successive hexane, chloroform and methanol extracts of the rhizome of Hedychium coronarium Koen. (HC) were subjected to evaluate analgesic and anti-inflammatory activities in animal model. In acetic acid-induced writhing test, the chloroform and methanol extract at doses of 400 mg/kg body weight elicited 27.23 and 40.59% inhibition of writhing reflex respectively. Both the chloroform and methanol extracts showed significant elongation of tail flick time (41.15 and 61.32% elongation respectively) at 400 mg/kg body weight. In carrageenan induced rat paw edema test, the chloroform and methanol extracts at a dose of 400 mg/kg body weight showed statistically significant (P<0.01) inhibition of paw edema by 27.46 and 32.48%, respectively at the third hour after carrageenan injection.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
|
pubmed:issn |
1011-601X
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
47-51
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pubmed:meshHeading |
pubmed-meshheading:17337428-Acetic Acid,
pubmed-meshheading:17337428-Analgesics,
pubmed-meshheading:17337428-Animals,
pubmed-meshheading:17337428-Anti-Inflammatory Agents,
pubmed-meshheading:17337428-Carrageenan,
pubmed-meshheading:17337428-Disease Models, Animal,
pubmed-meshheading:17337428-Edema,
pubmed-meshheading:17337428-Mice,
pubmed-meshheading:17337428-Pain,
pubmed-meshheading:17337428-Pain Measurement,
pubmed-meshheading:17337428-Pain Threshold,
pubmed-meshheading:17337428-Plant Extracts,
pubmed-meshheading:17337428-Rats,
pubmed-meshheading:17337428-Rats, Long-Evans,
pubmed-meshheading:17337428-Rhizome,
pubmed-meshheading:17337428-Time Factors,
pubmed-meshheading:17337428-Zingiberaceae
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pubmed:year |
2007
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pubmed:articleTitle |
Anti-inflammatory and analgesic effects of Hedychium coronarium Koen.
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pubmed:affiliation |
Department of Molecular and Cell Biology, College of Pharmacy, Seoul National University, Seoul 151-742, Korea.
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pubmed:publicationType |
Journal Article
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