Linked Life Data

17337214

Source:http://linkedlifedata.com/resource/pubmed/id/17337214

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-4-9
pubmed:abstractText
Veridical processing of biological movement is of immense value for adaptive behavior and social communication. Here we ask whether and, if so, how oscillatory cortical magnetoencephalographic (MEG) response to biological motion is modulated by early damage to periventricular regions that might affect the pathways interconnecting subcortical structures with cortex and cortico-cortical connectivity. The visual sensitivity to biological motion was lower in adolescents with periventricular leukomalacia (PVL). In controls, the evoked oscillatory MEG response (26.5 Hz) to biological motion peaked at a latency of 170 ms over the right temporo-parietal cortex. This increase was absent in PVL patients. By contrast, peaks in the oscillatory response to biological motion of lower frequency (23.5 Hz) were found in PVL patients later, at a latency of 290 ms over the left temporal region. The findings provide the first evidence for modulation of oscillatory cortical activity by periventricular lesions. The data suggest that PVL affects the brain connectivity with the right temporo-parietal cortex leading to disintegration of the neural network engaged in biological motion processing.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
1053-8119
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1256-63
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Oscillatory MEG response to human locomotion is modulated by periventricular lesions.
pubmed:affiliation
Department of Paediatric Neurology and Child Development, Children's Hospital, University of Tübingen Medical School, University of Tübingen, Tübingen, Germany. marina.pavlova@uni-tuebingen.de
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't