Source:http://linkedlifedata.com/resource/pubmed/id/17334246
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2007-4-6
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pubmed:abstractText |
High-mobility group box 1 (HMGB1) has been proposed as a late mediator of sepsis, but human data are sparse and conflicting. We describe plasma HMGB1 concentrations in humans with community-acquired pneumonia (CAP), the most common cause of severe sepsis, and test the hypotheses that HMGB1 levels are higher in CAP than healthy controls, higher in CAP with severe sepsis than CAP without severe sepsis, and higher in severe sepsis nonsurvivors than survivors.
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pubmed:grant | |
pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0090-3493
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
35
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1061-7
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:17334246-Aged,
pubmed-meshheading:17334246-Community-Acquired Infections,
pubmed-meshheading:17334246-Female,
pubmed-meshheading:17334246-HMGB1 Protein,
pubmed-meshheading:17334246-Humans,
pubmed-meshheading:17334246-Immunoblotting,
pubmed-meshheading:17334246-Intensive Care Units,
pubmed-meshheading:17334246-Male,
pubmed-meshheading:17334246-Pneumonia,
pubmed-meshheading:17334246-Prospective Studies,
pubmed-meshheading:17334246-Sepsis,
pubmed-meshheading:17334246-Severity of Illness Index
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pubmed:year |
2007
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pubmed:articleTitle |
Circulating high-mobility group box 1 (HMGB1) concentrations are elevated in both uncomplicated pneumonia and pneumonia with severe sepsis.
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pubmed:affiliation |
Clinical Research, Investigation, and Systems Modeling of Acute Illness (CRISMA) Laboratory, University of Pittsburgh, Pittsburgh, PA, USA. angusdc@upmc.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Research Support, N.I.H., Extramural
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