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rdf:type |
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lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0021267,
umls-concept:C0035918,
umls-concept:C0038995,
umls-concept:C0046579,
umls-concept:C0392747,
umls-concept:C0441889,
umls-concept:C1280500,
umls-concept:C1527116,
umls-concept:C1554963,
umls-concept:C1710133,
umls-concept:C1882417
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pubmed:issue |
7
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pubmed:dateCreated |
2007-5-3
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pubmed:abstractText |
Workers in the rubber industry are exposed to a complex mixture of hazardous substances and have increased risk of developing several diseases. However, there is no up to date survey examining the exposure in the Swedish rubber industry. One of the toxic compounds in the industry is carbon disulfide (CS(2)), which is biotransformed to 2-thiothiazolidine-4-carboxylic acid (TTCA). TTCA is used as a biomarker of CS(2) exposure, but there seem to exist inter- and intraindividual variability; which could partly be due to genetic variation. The aim of the study was to determine TTCA levels and the modifying effects of glutathione-related genes in a group of Swedish rubber workers.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0340-0131
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
80
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
589-98
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pubmed:meshHeading |
pubmed-meshheading:17333241-Adult,
pubmed-meshheading:17333241-Aged,
pubmed-meshheading:17333241-Air Pollutants, Occupational,
pubmed-meshheading:17333241-Female,
pubmed-meshheading:17333241-Genotype,
pubmed-meshheading:17333241-Glutamate-Cysteine Ligase,
pubmed-meshheading:17333241-Glutathione,
pubmed-meshheading:17333241-Glutathione Transferase,
pubmed-meshheading:17333241-Humans,
pubmed-meshheading:17333241-Industry,
pubmed-meshheading:17333241-Male,
pubmed-meshheading:17333241-Middle Aged,
pubmed-meshheading:17333241-Occupational Exposure,
pubmed-meshheading:17333241-Polymerase Chain Reaction,
pubmed-meshheading:17333241-Polymorphism, Single Nucleotide,
pubmed-meshheading:17333241-Rubber,
pubmed-meshheading:17333241-Sweden,
pubmed-meshheading:17333241-Thiazolidines
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pubmed:year |
2007
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pubmed:articleTitle |
Levels of 2-thiothiazolidine-4-carboxylic acid (TTCA) and effect modification of polymorphisms of glutathione-related genes in vulcanization workers in the southern Sweden rubber industries.
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pubmed:affiliation |
Division of Occupational and Environmental Medicine and Psychiatric Epidemiology, University Hospital, 221 85, Lund, Sweden. lena_s.jonsson@med.lu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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