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pubmed-article:17329344pubmed:abstractTextThe cellular immunity against Kaposi's sarcoma-associated herpesvirus (KSHV) is poorly characterized and has not been compared to T-cell responses against other human herpesviruses. Here, novel and dominant targets of KSHV-specific cellular immunity are identified and compared to T cells specific for lytic and latent antigens in a second human gammaherpesvirus, Epstein-Barr virus. The data identify a novel HLA-B57- and HLA-B58-restricted epitope in the Orf57 protein and show consistently close parallels in immune phenotypes and functional response patterns between cells targeting lytic or latent KSHV- and EBV-encoded antigens, suggesting common mechanisms in the induction of these responses.lld:pubmed
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pubmed-article:17329344pubmed:authorpubmed-author:WangFredFlld:pubmed
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pubmed-article:17329344pubmed:authorpubmed-author:BranderChrist...lld:pubmed
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pubmed-article:17329344pubmed:authorpubmed-author:BihlFlorianFlld:pubmed
pubmed-article:17329344pubmed:authorpubmed-author:HenryLeah MLMlld:pubmed
pubmed-article:17329344pubmed:authorpubmed-author:DollardSheila...lld:pubmed
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pubmed-article:17329344pubmed:volume81lld:pubmed
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pubmed-article:17329344pubmed:pagination4904-8lld:pubmed
pubmed-article:17329344pubmed:dateRevised2010-9-15lld:pubmed
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pubmed-article:17329344pubmed:year2007lld:pubmed
pubmed-article:17329344pubmed:articleTitleLytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes.lld:pubmed
pubmed-article:17329344pubmed:affiliationPartners AIDS Research Center, Massachusetts General Hospital East, 149 13th Street, Charlestown, MA 02129-2000, USA.lld:pubmed
pubmed-article:17329344pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17329344pubmed:publicationTypeComparative Studylld:pubmed
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