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rdf:type |
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lifeskim:mentions |
umls-concept:C0003320,
umls-concept:C0014644,
umls-concept:C0025260,
umls-concept:C0031437,
umls-concept:C0205245,
umls-concept:C0205263,
umls-concept:C0205275,
umls-concept:C0376526,
umls-concept:C0439680,
umls-concept:C0682456,
umls-concept:C0871161,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2348205,
umls-concept:C2911692
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pubmed:issue |
9
|
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pubmed:dateCreated |
2007-4-12
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|
pubmed:abstractText |
The cellular immunity against Kaposi's sarcoma-associated herpesvirus (KSHV) is poorly characterized and has not been compared to T-cell responses against other human herpesviruses. Here, novel and dominant targets of KSHV-specific cellular immunity are identified and compared to T cells specific for lytic and latent antigens in a second human gammaherpesvirus, Epstein-Barr virus. The data identify a novel HLA-B57- and HLA-B58-restricted epitope in the Orf57 protein and show consistently close parallels in immune phenotypes and functional response patterns between cells targeting lytic or latent KSHV- and EBV-encoded antigens, suggesting common mechanisms in the induction of these responses.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-10749966,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-10790138,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-10834968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11242051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11290599,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11489984,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11530315,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11927633,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11937579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-11967296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-12130505,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-12516570,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-12634388,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-12805431,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-14580882,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-14963115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15059848,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15060434,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15128832,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15155762,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15684323,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15797994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-15872023,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16028131,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16051815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16147978,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16393977,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16467198,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16496339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16547245,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16926293,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17329344-16991082
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-538X
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pubmed:author |
pubmed-author:BihlFlorianF,
pubmed-author:BranderChristianC,
pubmed-author:BrownElizabeth EEE,
pubmed-author:ChisholmJohn VJV3rd,
pubmed-author:DollardSheilaS,
pubmed-author:HenryLeah MLM,
pubmed-author:KaufmannDaniel EDE,
pubmed-author:KayeKenneth MKM,
pubmed-author:MartinJeff NJN,
pubmed-author:NarayanMurliM,
pubmed-author:ScaddenDavid TDT,
pubmed-author:SuscovichTodd JTJ,
pubmed-author:WangFredF,
pubmed-author:WelzelTania MTM,
pubmed-author:ZamanTauheed MTM
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pubmed:issnType |
Print
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pubmed:volume |
81
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4904-8
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pubmed:dateRevised |
2010-9-15
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pubmed:meshHeading |
pubmed-meshheading:17329344-Antigens, Viral,
pubmed-meshheading:17329344-Epitopes,
pubmed-meshheading:17329344-Herpesvirus 4, Human,
pubmed-meshheading:17329344-Herpesvirus 8, Human,
pubmed-meshheading:17329344-Humans,
pubmed-meshheading:17329344-Immunity, Cellular,
pubmed-meshheading:17329344-Immunologic Memory,
pubmed-meshheading:17329344-Immunophenotyping,
pubmed-meshheading:17329344-T-Lymphocytes,
pubmed-meshheading:17329344-Viral Proteins
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pubmed:year |
2007
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pubmed:articleTitle |
Lytic and latent antigens of the human gammaherpesviruses Kaposi's sarcoma-associated herpesvirus and Epstein-Barr virus induce T-cell responses with similar functional properties and memory phenotypes.
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pubmed:affiliation |
Partners AIDS Research Center, Massachusetts General Hospital East, 149 13th Street, Charlestown, MA 02129-2000, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study
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