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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8
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pubmed:dateCreated |
2007-5-14
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pubmed:abstractText |
Nitric oxide (NO) is a multifunctional molecule that is produced by both neuronal NO synthase (nNOS) and inducible NO synthase (iNOS), and the expression of nNOS and iNOS is up-regulated in various cancer cells, including cutaneous melanoma (CM). The authors hypothesized that selected functional single-nucleotide polymorphisms (SNPs) in the nNOS and iNOS genes are associated with the risk of CM.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0008-543X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1570-8
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17328085-Case-Control Studies,
pubmed-meshheading:17328085-Female,
pubmed-meshheading:17328085-Genetic Predisposition to Disease,
pubmed-meshheading:17328085-Humans,
pubmed-meshheading:17328085-Male,
pubmed-meshheading:17328085-Melanoma,
pubmed-meshheading:17328085-Nitric Oxide Synthase Type I,
pubmed-meshheading:17328085-Nitric Oxide Synthase Type II,
pubmed-meshheading:17328085-Polymorphism, Single Nucleotide,
pubmed-meshheading:17328085-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17328085-Risk Factors,
pubmed-meshheading:17328085-Skin Neoplasms,
pubmed-meshheading:17328085-Tumor Markers, Biological
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pubmed:year |
2007
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pubmed:articleTitle |
Polymorphisms of the neuronal and inducible nitric oxide synthase genes and the risk of cutaneous melanoma: a case-control study.
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pubmed:affiliation |
Department of Epidemiology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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