Source:http://linkedlifedata.com/resource/pubmed/id/17328074
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2007-3-21
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pubmed:abstractText |
Juvenile idiopathic arthritis (JIA) comprises several clinically distinct subgroups and is the most widespread cause of chronic childhood disability. A significant association between JIA and a polymorphism in the interferon regulatory factor 1 (IRF-1) gene has previously been reported, implicating IRF1 in disease susceptibility. The aim of this study was to replicate the IRF1 association in JIA using single-marker and haplotype analyses in a case-control study, using control subjects different from those in the previous study and a larger cohort of patients (n = 765).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
56
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
972-6
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pubmed:meshHeading |
pubmed-meshheading:17328074-Adolescent,
pubmed-meshheading:17328074-Adult,
pubmed-meshheading:17328074-Arthritis, Juvenile Rheumatoid,
pubmed-meshheading:17328074-Case-Control Studies,
pubmed-meshheading:17328074-Cohort Studies,
pubmed-meshheading:17328074-Gene Frequency,
pubmed-meshheading:17328074-Genetic Predisposition to Disease,
pubmed-meshheading:17328074-Genotype,
pubmed-meshheading:17328074-Haplotypes,
pubmed-meshheading:17328074-Humans,
pubmed-meshheading:17328074-Interferon Regulatory Factor-1,
pubmed-meshheading:17328074-Polymorphism, Single Nucleotide
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pubmed:year |
2007
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pubmed:articleTitle |
No evidence for genetic association of interferon regulatory factor 1 in juvenile idiopathic arthritis.
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pubmed:affiliation |
University College London, London, UK. m.fife@ucl.ac.uk
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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